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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS6
All Species:
22.12
Human Site:
S245
Identified Species:
48.67
UniProt:
Q9UKP5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKP5
NP_922932.2
1117
125273
S245
I
H
H
R
Q
K
R
S
V
S
I
E
R
F
V
Chimpanzee
Pan troglodytes
XP_526907
1117
125238
S245
I
H
H
R
Q
K
R
S
V
S
I
E
R
F
V
Rhesus Macaque
Macaca mulatta
XP_001084793
1117
125301
S245
N
H
H
R
Q
K
R
S
V
S
I
E
R
F
V
Dog
Lupus familis
XP_535255
1117
125043
S245
I
R
H
R
Q
K
R
S
V
S
I
E
R
F
V
Cat
Felis silvestris
Mouse
Mus musculus
P58459
1104
121067
T243
S
R
E
R
Y
V
E
T
L
V
V
A
D
K
M
Rat
Rattus norvegicus
Q1EHB3
1595
175796
Q314
M
K
G
D
D
H
P
Q
H
H
D
T
A
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513889
903
100601
S58
D
Q
N
G
A
F
L
S
F
T
V
K
S
D
R
Chicken
Gallus gallus
XP_424749
1118
125075
R245
S
S
H
S
R
Q
K
R
S
V
S
L
E
R
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923204
1116
124633
S244
G
A
H
R
Q
R
R
S
V
S
S
E
R
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
W261
V
A
T
W
Q
D
Q
W
E
D
V
I
E
R
K
Sea Urchin
Strong. purpuratus
XP_001180742
1320
148448
S363
Y
R
R
K
R
V
S
S
L
S
T
E
R
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.6
98.4
N.A.
59.7
30.4
N.A.
72.9
92.4
N.A.
82.8
N.A.
N.A.
N.A.
21.4
39.7
Protein Similarity:
100
99.9
99.7
98.9
N.A.
74.4
41.5
N.A.
75.7
95.8
N.A.
90.1
N.A.
N.A.
N.A.
31.1
54.6
P-Site Identity:
100
100
93.3
93.3
N.A.
6.6
0
N.A.
6.6
6.6
N.A.
73.3
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
33.3
13.3
N.A.
33.3
26.6
N.A.
80
N.A.
N.A.
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
10
0
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
10
10
0
0
0
10
10
0
10
10
0
% D
% Glu:
0
0
10
0
0
0
10
0
10
0
0
55
19
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
10
0
0
0
0
46
10
% F
% Gly:
10
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
28
55
0
0
10
0
0
10
10
0
0
0
0
0
% H
% Ile:
28
0
0
0
0
0
0
0
0
0
37
10
0
10
0
% I
% Lys:
0
10
0
10
0
37
10
0
0
0
0
10
0
10
10
% K
% Leu:
0
0
0
0
0
0
10
0
19
0
0
10
0
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
55
10
10
10
0
0
0
0
0
0
0
% Q
% Arg:
0
28
10
55
19
10
46
10
0
0
0
0
55
19
10
% R
% Ser:
19
10
0
10
0
0
10
64
10
55
19
0
10
0
0
% S
% Thr:
0
0
10
0
0
0
0
10
0
10
10
10
0
0
0
% T
% Val:
10
0
0
0
0
19
0
0
46
19
28
0
0
0
55
% V
% Trp:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _